BEST WESTERN PLUS of Wise

·From: The north. From Interstate 81, Exit 19 to Route 19 North. Travel approximately eight miles, turn left onto Highway 58. Approximately 45 miles, exit right onto US Highway 23 North. The BEST WESTERN of Wise is three miles directly on US Highway 23 on the right side of the highway. ·From: The south. From I-181, exit onto US Highway 23 North. Travel approximately eight miles, turn left onto Highway 58. Approximately 45 miles, exit right onto US Highway 23 North. The BEST WESTERN of Wise is three miles directly on US Highway 23 on the right side of the highway.The BEST WESTERN of Wise is across from Ridgeview Shopping Center at the intersection of US Highway 23 and Woodland Drive, adjacent to Reno's Roadhouse.